Insect bites appear hard nodule hyperplasia, this situation can be in the doctor’s guidance of local medication for anti-inflammatory, itching, swelling, but also with the corresponding oral medication. 1. Local medication: local medication includes topical hydrocortisone butyrate cream or mometasone furoate cream and other glucocorticosteroid creams, if there is obvious itching, you can also use glycerite lotion to stop itching, if there is oozing, you should also apply saline compresses and so on. 2. Oral medication: can also be used in conjunction with the use of ebastine, cetirizine and other antihistamines, if necessary, oral prednisone acetate and other glucocorticosteroid drugs. If the above symptoms continue without significant improvement, it is recommended to consult the hospital in a timely manner, under the guidance of a doctor to standardize the treatment, to avoid delays in the condition, the use of medication need to comply with medical advice.