Life is sometimes hardy and sometimes fragile. As the saying goes, the sky is unpredictable, and people have their own luck. There are various unpredictable risks on the operating table. As a surgeon, I am used to operating on patients and often reassure them that they are fine. But I often think, if one day I lie on the operating table, will I be able to face it, because I do not know whether I can wake up after a sleep under anesthesia, although the probability is very, very small, just like you know that flying is very safe, but every time you get on the plane will still be a little nervous. Here is the concept of sudden death, which is a sudden medical death. In a broad sense, any person who appears to be healthy in appearance or in the process of treatment for some non-fatal disease, and whose death occurs rapidly and unexpectedly due to an intrinsic lesion (organic or non-organic), is collectively referred to as sudden death or emergency death. The causes of sudden death are diverse, and the analysis of some previous cases of sudden death reveals that most of them are due to underlying diseases (e.g., cardiovascular and cerebrovascular pathologies) that were originally unknown to the organism. Only a few patients who died suddenly had no underlying disease (such as arteriosclerosis, vascular malformation, etc.) that caused sudden death, but the event that led to sudden death occurred “accidentally”. Once sudden death occurs, it is often difficult for the patient’s family to accept and medical disputes occur. In addition to sudden death caused by pre-existing underlying diseases, sudden death related to surgery may include the following: 1) sudden maternal death (amniotic fluid embolism) and fetal death (intrauterine asphyxia) during childbirth; 2) death due to air embolism during hepatic and cardiovascular surgery; 3) sudden death (pulmonary fat embolism) during orthopedic surgery; 4) mistakenly giving nitrogen gas as oxygen during anesthesia during surgery. 4, sudden death due to inhalation of nitrogen gas as oxygen (this probability rarely happens in regular hospitals); 5, sudden death due to low blood potassium in patients without attention during surgery (the heart stops beating when the blood potassium is low to a certain level); 6, sudden death once getting up and moving after a long period of bed rest after surgery (pulmonary artery embolism due to dislodged deep vein thrombosis in the lower limbs); 7, “accidental” death due to female cosmetic liposuction surgery (fat embolism) “Accidental” death (fat embolism); 8, sudden death during perioperative infusion (anaphylaxis is more). The doctor is kind, I believe that the majority of health care workers are dedicated to save patients. Although the chance of sudden death accident is rare, I hope to give the majority of medical and nursing staff a wake up call, in today’s complex doctor-patient environment, to minimize the occurrence of sudden death is the greatest degree of protection for both doctors and patients. Once the accident occurs, the doctor and patient should be resolved through legal means if there is a dispute. Autopsy is the most effective way to clarify the cause of death, to find the real “culprit”, is the best consolation for the deceased.