Paracetamol is acetaminophen, rifampicin and acetaminophen can be taken at the same time, you need to follow the doctor’s instructions for medication. The common dosage forms of rifampicin are capsules and tablets. Belonging to the rifamycin class of antimicrobials, this product is used in conjunction with other anti-tuberculosis drugs for tuberculosis, but also for non-tuberculosis mycobacteria, leprosy infections. Adverse effects of rifampicin can be seen as anorexia, epigastric discomfort, nausea, vomiting, and hepatotoxicity. Rifampicin is contraindicated in people who are allergic to the product or rifamycin analogs, biliary obstruction, severe hepatic insufficiency, and pregnant women within 3 months. Acetaminophen commonly used dosage forms such as tablets, belongs to the non-steroidal anti-inflammatory drugs, used for cold-induced fever, relief of mild to moderate pain. Adverse effects of acetaminophen can be seen as rash, itching, drug fever, urticaria, leukopenia, thrombocytopenia and so on. The drug is contraindicated in severe hepatic and renal insufficiency, hypersensitivity to the product. Rifampicin and acetaminophen instructions do not indicate the existence of drug interactions between the two, there is no contraindication, can be used together with medical advice.