The cause of acute leukemia in normal people suddenly is not clear, but it is related to chemical factors, physical factors, viral infections, genetic factors and other influencing factors. Acute leukemia is a malignant neoplastic disease of the hematopoietic system, mostly due to certain factors that damage the organism for a long period of time and eventually develop into leukemia, except that most of the onset of the disease is more acute, and the symptoms may appear suddenly and develop rapidly. The main factors that cause acute leukemia are as follows: 1. Chemical factors: frequent exposure to benzene compounds will increase the prevalence of leukemia, such as long-term exposure to poor-quality paints, frequent use of p-phenylenediamine-containing hair dyes, smoking and so on. 2. Physical factors: including X-rays, Y-rays and other ionizing radiation. When the human body is exposed to extremely high radiation levels, it is easy to develop acute leukemia. The prevalence of leukemia increases when the body is exposed to high levels of ionizing radiation, such as operators of medical imaging tests, researchers of ionizing radiation, and producers of electronic picture tubes, if they are not properly protected. 3. Viral infection: If infected with human T-cellophilic virus (HTLV-1), leukemia is also easily induced. 4. Genetic factors: If relatives in the family have a history of leukemia, the probability of the child developing leukemia will be higher than usual. The occurrence of gene mutations in the germ line, such as mutations in the CEBPA and RNUS1 genes, will also increase the prevalence of leukemia. If any of these factors are present, you should seek medical attention to identify the specific cause and follow the doctor’s instructions.