Generalized itching of liver and lung metastasis after bowel cancer surgery may be caused by jaundice caused by liver metastases, targeted/chemotherapy drugs or allergy. 1. Some patients with liver metastasis have jaundice symptoms due to compression of bile duct by the metastatic foci, which may be manifested as yellowing of skin and sclera, itching of skin, etc. At this time, glycerin lotion can be given to the patients. At this time, glycerine lotion can be given to relieve itching, and puncture drainage of bile can also be given to relieve the condition. 2. Treatment for primary foci and metastatic foci: chemotherapy, radiotherapy and interventional therapy can be given to control the foci and reduce the size of the foci, so as to improve the condition. 3. Some patients need to receive postoperative adjuvant therapy, such as targeted therapy, chemotherapy, etc., which may have adverse reactions such as skin itching. Such as cetuximab have skin reactions, etc., at this time need to give symptomatic treatment, serious need to stop the drug. 4. Allergic reaction or skin disease. In addition to the drug and the disease itself can cause itching, dermatologic diseases (neurodermatitis, etc.), food, drugs, mosquito bites, pollen allergies. In this case, anti-allergy medications are given, and exposure to allergens is stopped. Due to individual differences, the drug does not have the absolute most effective, need to be used in conjunction with their own situation under the advice of a doctor, the emergence of adverse drug reactions to timely medical treatment, drug allergies are prohibited.