Thyroid nodules can be associated with painful symptoms. Thyroid nodules are lesions caused by localized abnormal growth of thyroid cells. Most patients with thyroid nodules may have no obvious symptoms, but cystic nodules, if complicated by intracapsular hemorrhage, may increase in size faster in a short period of time and have localized pain. Therefore, patients with thyroid nodules may have symptoms of pain. In addition, patients with thyroid nodules may also have symptoms of abnormal thyroid function, such as hyperthyroidism, excessive sweating, emaciation, palpitations, fatigue and other symptoms, and hypothyroidism, chills, fatigue, weight gain and other symptoms. Patients with painful thyroid nodules are advised to go to the hospital and ask the doctor to make a judgment.