Whether the spots in the stomach are serious or not can not be generalized, the spots in the stomach may be caused by gastritis, and may also be caused by gastric ulcer, which is not very serious in general; and may be caused by gastric cancer, which is generally more serious. 1. Gastritis: spots on the surface of gastric mucosa may be caused by gastritis, superficial gastritis will be manifested as macular change of gastric mucosa, and atrophic gastritis can be manifested as white spot-like change of gastric mucosa, which is generally not serious. 2. Gastric ulcer: patients with gastric ulcer can also have leukoplakia-like changes in gastric mucosa, the leukoplakia area is sunken, surrounded by congestion, edema, dike-like elevation, and easy to bleed when touched, which is generally not serious. 3. Gastric cancer: gastric cancer can also appear spot-like changes on the gastric mucosa, or cauliflower-like lumps or ulcerative changes, which is more serious and needs to be treated as early as possible through surgery, chemotherapy, targeted therapy and other methods. In addition to the above diseases, other causes can also lead to spot-like changes in the patient’s gastric mucosa, and it is recommended to consult a doctor in time to find out the cause and ask the doctor to deal with it.