Most sepsis is not contagious, but it can be if it is caused by certain infectious pathogens. Sepsis is caused by the release of toxins due to a large number of bacterial attacks in the body, and the body produces many inflammatory mediators, which mix together to cause severe multi-organ failure in the body, It is unlike other infectious diseases such as hepatitis B, AIDS, syphilis, etc. The disease requires active search for the primary focus, surgery, broad-spectrum antibiotics, nutritional support, vitamin and micronutrient supplementation, and sometimes plasma and clotting factor transfusions. The disease has a high mortality rate and sometimes requires ventilator and ICU admission.