CT4N+M1 of gastric cancer indicates that the tumor has invaded the plasma membrane, visceral peritoneum and adjacent tissues, and is accompanied by distant metastasis. The staging of gastric cancer is mostly based on TNM staging, which mainly depends on regional lymph node metastasis, distant metastasis and the depth of infiltration of gastric wall. T4 in CT4N+M1 indicates that the stomach tumor has invaded the visceral peritoneum or the surrounding adjacent structures, while N indicates the number of lymph node metastasis in the surrounding area, and the larger the number after N indicates the more metastasis. M in CT4N+M1 of gastric cancer expresses whether the tumor has the tendency of distant metastasis or not, and M1 usually indicates the presence of distant metastasis, and the larger the value after the letter, the later the stage and the relatively poorer the prognosis. At present, clinical treatment for gastric cancer also needs to choose appropriate treatment programs based on TNM staging. For more questions about gastric cancer CT4N+M1, it is recommended to consult professionals for early treatment.