Wasting weight loss is a manifestation of weight loss due to wasting diseases, which can be seen in tuberculosis, diabetes, hyperthyroidism, etc. Many diseases can cause wasting, the most common ones such as diabetes, hyperthyroidism, tumors, etc. The harm that wasting brings to us should not be ignored, there are also problems caused by heavy exercise, poor diet and sleep, excessive mental stress, pay attention to check the specific situation. The following diseases are the causes of consumptive weight loss: 1, esophageal tumors Benign tumors of the esophagus are rare, smooth muscle tumors are the most common benign esophageal tumors, which can be multiple, but most patients have a good prognosis. Most primary esophageal malignant tumors are cancer. The most common esophageal malignancy is squamous epithelial carcinoma, followed by adenocarcinoma. Other malignant tumors of the esophagus include lymphoma, smooth muscle sarcoma, and metastatic carcinoma. Tuberculosis, commonly known as “consumption”, is a highly contagious chronic wasting disease caused by the invasion of Mycobacterium tuberculosis into the human body. It is not affected by age, gender, race, occupation or region, and many organs and systems in the human body can suffer from tuberculosis, of which pulmonary tuberculosis is the most common. More than 90% of TB infection is transmitted through the respiratory tract. TB patients are infected through coughing, sneezing, and loud noises that cause droplets with Mycobacterium tuberculosis to be sprayed out of the body and inhaled by healthy people. The typical manifestations are: cough, sputum, hemoptysis, chest pain, and difficulty in breathing. It is a chronic infectious disease with a long history of harming human health and has spread worldwide, causing millions of deaths. China is now one of the 22 countries with a high burden of tuberculosis worldwide, with the second highest number of tuberculosis cases in the world, second only to India. There are currently an estimated 2 million existing infectious tuberculosis patients in China. 3, pancreatic cysts Pancreatic cysts (pancreatic cysts) include true cysts, pseudocysts and cystic tumors. True cysts include congenital simple cysts, polycystic disease, dermatomal cysts, retention cysts, etc. The inner wall of the cyst is covered with epithelium. Cystic tumors include cystic adenoma and cystic carcinoma. The wall of pseudocysts is composed of fibrous tissue and is not covered with epithelial tissue. Clinically, pseudocysts are the most common in pancreatic cysts. Hairy cell leukemia (HCL) is a rare B-lymphocytic tumor, often characterized by complete blood cytopenia and splenomegaly, accounting for about 2% of all leukemias. Adenocarcinoma of small intestine is a malignant tumor from the mucosa of small intestine, mostly located around the papilla of duodenum, jejunum and ileum. It is one of the most common primary malignant tumors of small intestine. Among small intestine adenocarcinomas, those occurring in the duodenum tend to have early symptoms and are easy to diagnose and treat.