Diuretics used clinically mainly affect glomerular filtration, renal tubular reabsorption and secretion to achieve diuretic effect, but still mainly affect renal tubular reabsorption effect. Diuretics mainly refer to promoting the excretion of electrolytes and water molecules from the body and lowering the osmotic pressure to increase urine output. Diuretics promote the excretion of sodium ions and water, reduce blood volume, and reduce the volume load of the body, while effectively reducing the preload of the heart and relieving the pressure of the body circulation. Because of the increased sodium ion excretion in the organism, correspondingly more calcium ions are also excreted, because in the pathological situation it is isotropic conversion, the intracellular calcium ions are reduced, the tension of the blood vessel wall is decreased, the cardiac excretion is increased, and the blood supply of the organism is improved. Diuretics also have a very important role in delaying myocardial remodeling and inhibiting the damaging effects of parasympathetic nerves on the heart.