The male glans mucosa is rich in nerve endings, the main role is to feel sexual stimulation, thus inducing sexual excitement. For men, if the foreskin glans is excessively sensitive, there are usually the following reasons: 1. if suffering from inflammation of the glans, it will cause an increase in glans sensitivity; 2. is the penis itself when the sensitivity is high, smaller stimuli will cause sexual excitement resulting in orgasm, this situation is generally common in patients with premature ejaculation. Premature ejaculation patients tend to have a short sex life due to overly sensitive penile nerves, which affects the quality of men’s sex life, and for this condition treatment is generally required. If the application of anti-sensitive drugs applied to the glans to reduce the sensitivity of the glans can achieve the purpose of treatment of premature ejaculation, such as commonly used are lidocaine cream.