The causes of redness and peeling at the corners of the mouth are as follows: 1. Stomatitis: redness and peeling at the corners of the mouth, accompanied by itchy symptoms, and in severe cases, dryness and cracking, are mostly seen clinically in stomatitis, which is an allergic skin disease. In terms of treatment, the first thing you need to do is to have a balanced diet, consume more vegetables and fruits, etc., and correct the habit of partial eating, especially for adolescents in their formative years. If mild erythema and peeling occurs, this can be done with the application of gentamycin eye ointment. If the corners of the mouth erythema is increasing, and accompanied by serious peeling, and even dry crack, then you can choose tacrolimus ointment and urea vitamin E cream mixed topical, but also oral compound glycopyrrolate tablets and imipramine slow-release tablets. 2, burns: the corners of the mouth red, peeling, but also can be considered for burns caused by inflammatory changes in the skin of the lips, then you can ice after mixed topical erythromycin ointment and pimecrolimus This can be done with a mixture of topical erythromycin eye ointment and pimecrolimus cream after icing. During the treatment period, you need to avoid spicy and stimulating food, alcohol, rest and stay up late. At the same time, you must pay attention to the care of the skin around the corners of the mouth, you can often use topical lip balm, but also need to protect the sun.