Renal failure requires symptomatic treatment, primary treatment, nutritional support therapy and renal replacement therapy. 1. Symptomatic treatment: for the complications such as anemia, hypertension, hyperkalemia, acid-base imbalance, etc., it is necessary to correct anemia with osteotriol etc., lower blood pressure with hydrochlorothiazide etc., lower potassium with calcium gluconate, diuresis etc., and correct acid substitution with sodium bicarbonate sedation. 2. Nutritional supportive treatment: low protein diet is needed in daily diet, such as eggs, milk, lean meat, fish and so on. In addition, it is also necessary to supplement vitamins, folic acid and other nutrients. 3. Treatment of primary disease: glucocorticoids such as prednisone and other immunosuppressants such as cyclophosphamide and rituximab can be applied to the primary disease. 4. Renal substitution therapy: the main applicants are those who have chronic kidney disease stage 4 or above or need to receive dialysis within 6 months. It mainly includes hemodialysis, peritoneal dialysis and kidney transplantation. Kidney failure needs to be treated strictly under the guidance of doctors, and the above drugs should be used under the guidance of doctors.