Women without sex for a long time may lead to the emergence of endocrine disorders, menstrual disorders, prone to acne spots and so on. 1. Endocrine disorders: long-term suppression of libido may affect the human nervous system, leading to irritability, excessive sweating, insomnia symptoms. 2. Menstrual disorders: women’s menstruation is related to estrogen secretion. Long-term absence of sex may reduce the secretion of sex hormone, which may lead to menstrual disorders, abnormal bleeding, prolonged menstrual period, menstrual cramps and other adverse effects. 3. Easily appear acne spot: long-term no sex life, may lead to women’s skin is easy to dull and yellow, long color spots, and so on. Women should pay attention to maintaining a good state of mind, regular outdoor exercise, and appropriate recreational activities, such as running and yoga, to maintain the body in a healthy state. If any physical discomfort occurs, it is recommended to seek timely medical treatment.