Progesterone is needed for luteal support after embryo transfer of assisted reproduction. Angiotensin capsule is a progesterone drug commonly used for vaginal administration. Watery discharge after vaginal plugging of Angiotensin has two causes: first, drug side effects, vaginal itching in some patients after medication, drug residues are not absorbed and accumulated resulting in increased vaginal discharge, which does not need treatment. Secondly, vaginitis caused by pathogenic bacteria invasion due to inattentiveness in daily life or poor body resistance may result in watery discharge, increased leucorrhea and odor. During vaginal administration, it is important to cut the nails and wash hands carefully and gently before administering the medicine, so as not to damage the vaginal mucosa and to wear clean gloves to prevent infection by pathogenic bacteria.