Vitamin B6 is a trace element that exists in the body and can be taken through food, and this vitamin itself does not directly inhibit sebum secretion. However, it can regulate the body’s nervous system to a certain extent, so that its neuroregulatory functions are in a stable state, which can reduce the secretion of sebaceous glands to a certain extent and achieve the purpose of inhibiting sebum secretion. The condition has a certain auxiliary therapeutic effect on states such as insomnia, dreaminess, irritability and depression, and it can regulate the immune metabolic function of the skin to a certain extent. For oily skin or people who are very prone to acne, it has a good auxiliary treatment effect. However, the effect of simply choosing vitamin B6 is not particularly good, and it can be combined with the use of topical adapalene gel, or oral retinoic acid, which will have a more ideal effect on the control of seborrhea.