The face is characterized by full, smooth and symmetrical curves as a natural, youthful and beautiful expression. The decrease in the fullness and atrophy of the soft tissues of the face will give a visual impression of old age and emaciation. Using minimally invasive injections of fat or hyaluronic acid to restore the original volume of soft tissues in the middle of the face, so that the face has a three-dimensional and full soft tissue contour again, is a common treatment in outpatient clinics nowadays. Today, we will compare the respective characteristics of the two filling methods, fat and hyaluronic acid, which can be referred to by the majority of medical practitioners when seeking medical treatment. Through the above chart, I believe you have a certain understanding of the respective advantages and disadvantages of autologous fat filler and hyaluronic acid filler. The patients can make a choice according to their own situation. Finally, we would like to remind the majority of medical seekers that the “hyaluronic acid” claimed to be cheap by illegal institutions is mostly fake medicine, and hyaluronic acid injection must be chosen in regular medical institutions to prevent the trap of “three no treatment”, otherwise the consequences are unthinkable.