If there is pain in the lower abdomen when holding in urine, it may be accompanied by cystitis, interstitial cystitis, bladder stones, or bladder tumors, chronic urinary retention and other diseases. It is recommended that patients go to the hospital for relevant examinations to further clarify. Firstly, chronic cystitis or interstitial cystitis is most common in women. It can cause patients to have pain in holding urine, accompanied by frequent urination, urinary urgency, or accompanied by painful urination. Urine routine examination, cystoscopy, or bladder water dilatation examination can be carried out to further exclude. Secondly, if there are bladder stones, the state of holding urine can also cause pain in the bladder area, that is, abdominal pain and swelling. It can also be accompanied by interruption of urination, or symptoms of urinary frequency and urgency. Need to carry out ultrasound examination of the urinary system, to further exclude. Third, when suffering from bladder tumors, chronic urinary retention, can appear to have to hold urine when the small abdominal pain. It can also be accompanied by poor urination, bleeding in urination, or accompanied by lumbar pain and fever. It is recommended to carry out cystoscopy, CT examination of the urinary system to further exclude the presence of related diseases.