The pain in the middle of the chest when getting up may be related to diseases of the locomotor system, diseases of the circulatory system, respiratory system and other reasons. 1. Diseases of the locomotor system: such as costochondritis, when getting up and taking action, it can cause inflammation to stimulate the chest wall, and the phenomenon of pain in the middle of the chest appears. 2. Circulatory system diseases: such as coronary heart disease, can be triggered by physical labor or emotional excitement, often feel the pressure behind the sternum or precordial area, tightness, chest heaviness. 3. Respiratory diseases: such as pleurisy, when pathogens such as tuberculosis bacillus invade the pleura, it can cause local inflammatory reaction and chest pain. It is recommended that people who have pain in the middle of the chest when getting up go to the hospital in time to clarify the cause of the disease and carry out standardized treatment under the guidance of the doctor.