It is obvious and understandable that Coke, as a carbonated beverage commonly used in daily life, has some killing effect on sperm in vitro, but there is no scientific basis for the killing effect on sperm in vivo. The cola consumed and absorbed from the digestive tract does not directly affect the spermatogenic function of the testes, nor is it directly harmful to the spermatozoa in the epididymis that are in the process of maturation. Long-term, heavy consumption of cola, as a carbonated beverage, may be harmful to the function of the gastrointestinal tract, but there is no scientific research to confirm whether it is potentially harmful to the spermatogenic function.