Manganese external application can reduce edema, reduce the oozing around pancreatitis, and facilitate the recovery of the condition. Acute pancreatitis patients will appear around the pancreas with oozing, seepage, pancreas with edema, usually patients will have abdominal pain, distension, as well as the possibility of affecting the gastrointestinal function of peristalsis, the patient will have abdominal distension, the anus stops defecation, the main symptom is in the periphery of the pancreas, usually need to fast and fasting, gastrointestinal decompression, anti-infectious, inhibit the pancreas pancreatic enzyme secretion, rehydration of the fluid to symptomatic treatment. If the patient’s abdominal pain, abdominal distension is more obvious, you can use mannite on the outside of the skin externally, can reduce edema, reduce the exudation around the pancreas, and is conducive to the recovery of gastrointestinal function.