Laparoscopic Gastric Cancer Surgery

  Since 1994, when Kitano first reported laparoscopic radical surgery for early gastric cancer in Japan, laparoscopic gastric cancer surgery has been gradually performed in Japan and abroad. 1997, Goh et al. adopted laparoscopic D2 radical surgery for progressive gastric cancer, thus expanding the indications for laparoscopic radical surgery for gastric cancer from early gastric cancer to earlier progressive gastric cancer. 2002, Hashizume et al. Hashizume et al. first reported the da Vinci robotic surgical system assisted radical gastric cancer surgery. After more than 10 years of development, more and more units have been performing laparoscopic gastric cancer surgery, and the number of reported cases has gradually increased.  Laparoscopic surgery for early gastric cancer Laparoscopic surgery for early gastric cancer is a more mature technique, and its recent efficacy is better than that of open surgery, and its long-term efficacy is comparable to that of open surgery. In a multicenter study in Japan, 1249 patients with early gastric cancer were treated with laparoscopic surgery, and the median follow-up time after surgery was 36 months, and only 6 patients recurred. 5-year tumor-free survival rate was 99.8% for stage IA, 98.7% for stage IB, and 85.7% for stage II. Therefore, laparoscopic surgery for early gastric cancer has become one of the standard procedures for gastric cancer statute in Japan.  Laparoscopic surgery for progressive gastric cancer Laparoscopic surgery for progressive gastric cancer is currently the focus and hot spot of clinical research on laparoscopic gastric cancer surgery. Early gastric cancer accounts for more than 70% of all gastric cancers in Japan, while progressive gastric cancer is the main cancer in China and some European and American countries. The Japan Gastric Cancer Association guidelines have made laparoscopic gastric cancer D2 radical surgery a new clinical research treatment option for early stage progressive gastric cancer, mainly treating gastric cancer patients within T2N1 stage. While the proportion of surgery for progressive gastric cancer in China, some European and American countries is about 50-80%, there are also patients with stage IIIB and some stage IV gastric cancer treated by laparoscopic radical gastric cancer surgery.  In recent years, more and more units at home and abroad have carried out laparoscopic surgery for progressive gastric cancer, and whether laparoscopic surgery can achieve the curative effect of progressive gastric cancer is still an important topic of clinical exploration. Among them, the extent of lymph node dissection and the average number of lymph node dissection are still the focus of doubt and concern of many scholars. The results of domestic and international studies have shown that laparoscopic D2 radical surgery for progressive gastric cancer is technically feasible, and the differences in the complete resection of gastric cancer, the extent of resection of sufficient normal tissues around the tumor and the number of lymph node dissection are not statistically significant when compared with open surgery, and can achieve the curative effect on progressive gastric cancer.  There is no prospective randomized controlled study on the long-term clinical efficacy of laparoscopic surgery for progressive gastric cancer in a large number of cases. However, some single-center prospective randomized controlled studies and a large number of retrospective studies have shown that laparoscopic radical treatment of progressive gastric cancer can achieve long-term outcomes comparable to those of open surgery. The long-term outcomes after laparoscopic progressive gastric cancer surgery still need to be concluded from a multicenter clinical prospective randomized controlled study with a large number of cases.  Currently, the KLASS01 study in Korea and the CLASS01 study conducted by Prof. Guosin Li in China are large multicenter prospective clinical studies comparing the efficacy of laparoscopic and open gastric cancer surgery, and more evidence-based medicine is expected.  New laparoscopic gastric cancer surgery Single-port laparoscopic gastric cancer surgery. Omori et al. reported 7 patients with early gastric cancer underwent transumbilical single-port laparoscopic radical distal gastrectomy with a 2.5 cm umbilical incision, placement of 3 trocar, and 3 laparoscopic gastric free + D1 + β lymph node dissection + digestive tract reconstruction. In China, Jiang et al. reported gastric sinus cancer using transumbilical single-port laparoscopic surgery, all with good recent results.  Gastric cancer surgery with da Vinci robotic surgery system The da Vinci robotic surgery system ensures the completion of high-quality radical gastric cancer surgery with its intelligent and humanized control system, high-definition three-dimensional image system and more stable and flexible operating system. There are many reports about the da Vinci robotic surgery system performing gastric cancer surgery both at home and abroad, and the recent results are good.  Current problems China is dominated by progressive gastric cancer, and the proportion of early gastric cancer detection is low. Laparoscopic D2 radical surgery for gastric cancer is equivalent to laparoscopic surgery for early gastric cancer, which is more difficult to operate and has a longer learning curve. It is relatively more difficult to operate and has a longer learning curve.  To improve the diagnosis rate of early gastric cancer and actively carry out laparoscopic surgery for early gastric cancer, it is necessary to establish laparoscopic gastric cancer surgery operation specification and professional training base for laparoscopic gastric cancer surgery, and at the same time, clinical multicenter large sample prospective randomized controlled study of laparoscopic progressive gastric cancer surgery and related basic research should be vigorously carried out, so as to improve the overall level of laparoscopic gastric cancer surgery in China.