The high incidence of liver cancer in China is mainly attributed to the title of hepatitis, from chronic hepatitis to cirrhosis to liver cancer, the large sample of cirrhosis to liver cancer indicates that the cancer rate is relatively high. Most of the cirrhosis into hepatocellular carcinoma is nodular hepatocellular carcinoma at the beginning, which is commonly known as small hepatocellular carcinoma, and it is only when it is unconsciously allowed to develop to the point of having symptoms that it is examined to be massive hepatocellular carcinoma or even diffuse hepatocellular carcinoma, which loses the time for early surgery and other effective treatments, so early detection of cirrhosis into hepatocellular carcinoma is very, very important. It is reported that tenofovir treatment for hepatitis can achieve 74% reversal of cirrhosis after five years, but in fact cirrhosis is a chronic liver disease that can not be reversed, and only through antiviral and liver protection therapy to block the liver’s continued tissue proliferation, to avoid its continued deterioration. Long-term antiviral therapy can reduce the incidence of liver cancer. Slowing the progression of the disease. The choices of antiviral therapy drugs are lamivudine, tibivudine, adefovir, entecavir, and pranofovir, etc., which must be chosen under the guidance of a senior liver specialist.