The most effective drugs for smoking cessation are the following: 1. Anti-anxiety and anti-depressant drugs, the most effective of which is bupropion, which can effectively relieve the withdrawal reactions caused by smoking cessation, such as anxiety, irritability, nervousness, conflicts with people, and can also relieve the physical discomfort caused by smoking cessation, such as headaches, dizziness, nausea, vomiting, uncomfortable body, and even a feeling of insect bites all over the body. 2, may also use Chinese medicine to help treat, such as commonly used is on the nine flavor Zhenxin granules or tranquilizing brain liquid, these drugs can also alleviate the various physical discomfort caused by smoking cessation, mood irritability. 3, can also take vitamins to relieve anxiety, upset, etc., to quit smoking treatment, commonly used are glutathione and vitamin B1.