Loss of smell in the nose is considered to be caused by nasal polyps, sinusitis, nasal tumors and other diseases. According to different causes, patients can follow the doctor’s instructions to use general treatment, drug treatment, surgical treatment and other ways of treatment. 1. Nasal polyps: If the patient’s nose loses the sense of smell due to nasal polyps, the patient can follow the doctor’s instructions to use local glucocorticoid sprays, such as budesonide nasal spray, mometasone furoate nasal spray and so on, to play an anti-inflammatory effect. If you have multiple, recurrent nasal polyps, you can follow the doctor’s instructions for surgical treatment, such as nasal endoscopic surgery. 2. Sinusitis: If the nose loses the sense of smell due to sinusitis, patients should keep the nasal cavity clean and choose sensitive antibiotic treatment according to the drug sensitivity test after clarifying the causative organisms, e.g., anaerobic infections can be treated with antibiotics such as metronidazole and tinidazole as prescribed by the doctor, to achieve the anti-inflammatory effect. 3. Nasal tumor: If the loss of smell is caused by nasal tumor, patients can follow the doctor’s instructions for surgical treatment, and if necessary, local radiotherapy and other auxiliary treatments should be carried out. It is suggested that patients who have lost their sense of smell should go to the hospital for medical consultation to clarify the cause of the disease and follow the doctor’s instructions to standardize the medication and treatment.