When alcohol is drunk, it first enters the stomach and mixes with stomach acid, then enters the intestine via the pylorus under the action of gastric peristalsis, and is absorbed into the circulation in the epithelial cells of the small intestine mucosa. 10% of the alcohol entering the circulation is excreted in the form of sweat and inhalation, while the remaining 90% enters the liver, the body’s chemical plant, for processing. The liver metabolizes ethanol in two steps and the corresponding conversion enzymes – the first step is the conversion of ethanol into acetaldehyde by ethanol dehydrogenase (ADH), which is the main cause of nausea, vomiting and other signs of intoxication; the second step is the conversion of acetaldehyde into acetic acid by acetaldehyde dehydrogenase (ALDH), which is a substance produced by the body’s normal metabolism The second step is the conversion of acetaldehyde into acetic acid, a substance produced by the body’s normal metabolism, and its final breakdown into carbon dioxide and water. About 50% of Chinese people have a weakly active subtype of ALDH gene, so after drinking a large amount of acetaldehyde accumulates in the body, and before it is metabolized by the liver, other organs of the body will be affected by it, such as the blood vessels of the whole body will be dilated and blood pressure will drop under the effect of alcohol. While low concentrations of alcohol have an excitatory effect on the brain (gabbing and brotherhood), at high concentrations it manifests itself as an inhibitory effect (incoherent speech and failure to recognize north and south).