The pain of hard lumps growing at the junction of thigh and scrotum is considered to be more likely to be lymphadenitis, sebaceous cyst infection, lipoma, fibroma, which can be diagnosed by combining the symptoms as well as relevant auxiliary examinations. 1. Lymphadenitis: it is mostly caused by bacterial infection in the affected area and surrounding tissues and organs. Besides the swelling and pain of lymph nodes, there are many infected foci in the vicinity with symptoms of redness, swelling, heat and pain. 2. Sebaceous cyst infection: the opening of sebaceous gland ducts is blocked, and the internal secretion can not be discharged, which leads to the formation of sebaceous cysts. When sebaceous cysts are infected, it can be manifested as hard lumps in the affected area, accompanied by pain. 3. Lipoma, fibroma: benign tumors, slow-growing, but painless, part of the patient involved in the nerve can also appear pain. Thigh and scrotum junction long hard lump pain, it is recommended to go to the hospital to improve the auxiliary examination, such as ultrasound, in order to clarify the diagnosis.