Intercostal neuralgia is mainly manifested as local radiating pain in the chest and back, and the causes of corresponding pain are mainly related to diseases, and the common causes include herpes zoster, trauma, osteophytes and tumors. 1. Herpes zoster: Herpes zoster virus can cause damage to the nerves, causing nerve edema, and then a series of sequelae will occur, causing intercostal neuralgia. 2. Trauma: Trauma directly damages the intercostal nerves, which will lead to intercostal neuralgia. 3. Bone metaplasia: caused by degenerative changes, the bone metaplasia will compress the nerve and cause intercostal neuralgia. 4. Tumor: Tumor-like lesions can also cause intercostal neuralgia when they compress and invade the peripheral nerves. If the intercostal neuralgia is obvious and cannot be relieved, it is necessary to consult a doctor in time for observation and standardized treatment under the guidance of the clinician after confirming the diagnosis of the disease.