Intrahepatic cholestasis can be caused by a variety of factors and can be treated with medication, endoscopy or surgery.
1. Drug treatment: intrahepatic cholestasis may be caused by autoimmune disease or drug-related liver injury. Generally, ursodeoxycholic acid and other drugs can be used as prescribed by the doctor to alleviate the localized cholestasis. Hormonal drugs (glucocorticoids) and hepatoprotective drugs (e.g. compound glycyrrhizin) can also be applied.
2. Endoscopic treatment: For cholestasis caused by primary sclerosing cholangitis, endoscopic treatment can be carried out by placing an internal stent in the stenosis and dilating the narrowed section of bile duct with a probe.
3. Surgery: Intrahepatic cholestasis may be caused by bile duct stones, and surgery (such as partial hepatectomy, endoscopic retrograde cholangiopancreatography and lithotripsy) can be used to relieve biliary obstruction, remove infected foci, eliminate stones, and smooth bile drainage according to the doctor’s instructions.
In addition, if self-exempted liver and sclerosing cholangitis lead to long-term intrahepatic biliary stasis, it can cause cirrhosis, in which case liver transplantation should be performed for treatment.
Patients with intrahepatic cholestasis should consult a doctor in time and follow the doctor’s instructions to do the appropriate treatment.