People with seafood allergy should eat oyster sauce with caution; and patients with gout, high blood pressure and kidney disease need to eat less oyster sauce. 1. Because oyster sauce is oyster oil made from oysters, it is an additive, so seafood allergy is not recommended to eat oyster sauce to avoid allergies. 2. Generally every 100 grams of oyster sauce contains more than 200 milligrams of purine, if gout patients long-term or large amounts of food may lead to elevated uric acid, triggering or aggravating the condition. 3. Because oyster sauce contains more salt, and people with high blood pressure should be low-salt, low-fat, low-cholesterol diet, so hypertensive patients need to eat less oyster sauce. 4. Oyster sauce contains a large amount of sodium, excessive intake will destroy the osmotic pressure balance in the body, which can cause edema in severe cases. Excessive intake of sodium in patients with kidney disease will increase the burden on the kidneys and may aggravate the condition. It is recommended that special populations consult a dietitian and physician for guidance on scientific diet.