If the patient feels chest tightness and shortness of breath while lying down and feels relief after maintaining a sedentary position, this condition is highly considered to be caused by heart failure. Patients are advised to combine diuresis and vasodilation to improve symptoms. Patients may also have cardiac neuropathy or disturbances in the regulation of vegetative nerves, which may cause similar discomfort. In addition, some patients may have pulmonary occupancy and a large amount of fluid in the chest cavity bilaterally, which may cause chest tightness and shortness of breath when lying down, and this condition will be slightly relieved when sitting up. Patients are advised to combine with closed chest drainage if necessary. In addition to this, patients are advised to combine oxygen therapy and to pay attention to finding the cause, which can be done with preliminary screening of lung CT, cardiac ultrasound and BNP.