Children with enlarged tonsils with white spots and fever may be seen in acute upper respiratory tract infections, diphtheria and other diseases, more general treatment and drug therapy. For children with fever when the temperature <38.5 ℃ can be used to apply warm water to the forehead, reduce the wearing of clothing and other physical methods to cool down, and drink more water; when the temperature exceeds 38.5 ℃ also need to use ibuprofen, acetaminophen and other antipyretic drugs under the guidance of a doctor. For acute upper respiratory tract infections, it is necessary to pay attention to rest, ensure adequate sleep, maintain a certain temperature and humidity in the room, and pay attention to indoor air circulation. There is no special medication for viral infections. If it is caused by bacterial infection or combined with bacterial infection, it can be treated with cefixime, cefaclor, amoxicillin and other drugs as prescribed by the doctor. In the case of diphtheria, children need to be hospitalized and isolated because it is an acute infectious disease; it can cause complications such as myocarditis and requires bed rest for at least 2 weeks. During the period of illness, fluid nutrition should be supplemented with easy-to-digest food, and the room should be kept at a certain temperature and humidity. It is necessary to use antitoxin treatment as early as possible; antibiotics preferred penicillin, penicillin allergy can be erythromycin, azithromycin and other drugs treatment. All of the above drugs need to be used under the guidance of a doctor, avoid self-medication. When the child has fever, cough, sore throat and other discomforts, it is recommended to consult a doctor in time to be evaluated and handled by a specialist to avoid delaying the condition.