Hyporegulation is a procedure performed for IVF. The purpose of down regulation is to suppress pituitary gland down regulation or to reduce spontaneous luteinizing hormone spikes, to avoid spontaneous ovulation, to proactively address the timing of HCG administration and egg retrieval, to increase the number of follicle recruitment and to improve the synchronization of follicle development by using the initial short-term boost of GN secretion by the medication, and to obtain more synchronized follicles to match the overall IVF process. There are two ways to perform down regulation, taking birth control pills such as Mafron and taking down regulation injections such as Tamiflu. During the down regulation period, there are dietary requirements, a general diet with less fried and stimulating food, supplementing with vegetables and fruits, drinking more water is very necessary, and doing a moderate amount of outdoor exercise to strengthen the resistance.