Sequelae of facial paralysis are mainly treated with medications such as vitamin B1, surgical treatment, and physical therapy. Sequelae of facial paralysis are mainly symptoms such as distorted mouth and eyes, shallow nasolabial folds, inability to close the eyes, and tearing that remain after acute treatment, which can be caused by untimely treatment of facial paralysis, unsatisfactory treatment effect, improper treatment method, and more serious condition. The treatment of facial paralysis sequelae can be applied under the guidance of physicians with local injection of botulinum toxin type A to relieve spasm, vitamin B1 and other B vitamins to nourish nerves and promote nerve repair. If necessary, surgical treatment such as stapedial tendonectomy can be performed. At the same time, appropriate physical therapy such as hot compresses, massage, and acupuncture to improve local circulation and promote the recovery of symptoms. It is recommended that the patient actively seek medical treatment and follow the doctor’s instructions for medication.