Betalucil and sotalol are not recommended to be taken at the same time. Betalucil is metoprolol tartrate, which, like sotalol, is a beta-blocker and is used for hypertension, angina pectoris, myocardial infarction, and a variety of cardiac arrhythmias. The difference is that metoprolol is a selective beta 1 receptor blocker and has a greater ability to inhibit myocardial contractility. When metoprolol and sotalol are taken at the same time, they both act on beta receptors and do not work synergistically, while the adverse effects of the drugs will be superimposed on each other, such as bradycardia, hypotension, bronchospasm, etc., and in severe cases, it may lead to worsening of cardiac arrhythmias and heart failure. Therefore, when metoprolol or sotalol alone is not effective in the treatment of arrhythmia or hypertension, it can be combined with other types of drugs such as calcium channel blockers, angiotensin-converting enzyme inhibitors, etc., which can produce synergistic effects. It is recommended that patients take standardized treatment under the guidance of a professional doctor, and should not take medication privately.