In clinical practice, symptoms such as chest pain and shortness of breath are not uncommon, and although the big chance to consider heart and lung diseases, there are many patients who can’t find any problems in the examination, but their symptoms are getting worse day by day. ECG – no abnormality Cardiac color – no abnormality CT – no abnormality Imaging – no abnormality The heart is not an autonomous The heart is not an autonomous entity, its activities are subject to the innervation of the higher centers of the brain, the brainstem, and the lower centers of the spinal cord. In the process of conduction of this order, it needs to pass through the spinal cord and cervicothoracic ganglion, and it is important to know that the lower centers of sympathetic nerves are located in the lateral horns of the spinal cord, and that the preganglionic fibers of the sympathetic nerves are myelinated fibers that follow the anterior root of the spinal nerves of this segment through the foramen ovale to the visceral ganglion. The postganglionic fibers are distributed along three pathways: 1) along with the spinal nerves, 2) entangled in blood vessels and distributed along with the vascular route, and 3) directly to the viscera. The function of sympathetic nerves is to counteract the parasympathetic nerves and regulate and balance each other to maintain the normal function of organs. If the sympathetic nerve is stimulated or damaged due to compression or pulling caused by spinal instability, subluxation, herniated intervertebral discs, calcification of the primordial zone or bone spurs, it can cause autonomic dysfunction, and many organ and visceral symptoms will appear. For example, cervical spondylosis can cause head, eye, ear, nose and throat symptoms, because the vertebral artery supplies blood circulation to the brainstem and occipital lobe optic center. Postganglionic fibers emanating from the upper cervical sympathetic ganglion are distributed to the eye and carotid plexus, regulating ocular circulation and pupil-dilating and oculofacial muscles. The upper cervical sympathetic ganglion is located in front of the cervical to cervical 3 transverse process. When the upper cervical vertebrae are misaligned, the transverse process is also shifted, which can involve and stimulate the upper cervical sympathetic ganglion, causing symptoms in the eye or other organs of the fifth house. The eastern part of the spinal cord in the cervical spinal cord can also be stimulated by the misalignment of the occipital atlantoaxial joint, causing periocular neuralgia or frontal pain. Damage to the carotid plexus can lead to ocular circulatory disorders resulting in retinopathy. The various symptoms may occur because of problems in the following areas. The cervical sympathetic ganglion has a cardiac branch innervating the heart, and the cervical sympathetic ganglion originates from the 1st and 2nd thoracic sympathetic ganglion’s white traffic branch. Sinus tachycardia and palpitations can occur in the case of upper cervical spine instability and misalignment; bradycardia often occurs in the case of misalignment of cervical vertebrae from cervical vertebrae from cervical vertebrae 4 to cervical vertebrae 6; misalignment of cervical vertebrae from cervical vertebrae 7 to thoracic vertebrae 2 is often observed in atrial fibrillation; and misalignment of vertebrae from thoracic vertebrae 3 to thoracic vertebrae is commonly seen in the case of ventricular, atrial premature contractions, and AV blocks. Recent studies have shown that stimulation of the cervical 7 nerve root can cause chest and axillary pain in subjects, and stimulation of the cervical 7 and 8 nerve roots can cause spasm of the pectoralis major muscle. Most of the right sympathetic nerve fibers end up in the sinoatrial node, while most of the left fibers end up in the atrioventricular node and atrioventricular bundle. After the sympathetic preganglionic fibers are compressed and low-functioning, the parasympathetic nerves become relatively excited, and spasmodic contraction of coronary arteries occurs, which can lead to anginal episodes. If a rotational subluxation of the spine occurs, this bony stimulus is biased to one side and will result in arrhythmias due to the presence of cardiac off-points. With regard to the simultaneous presence of chest tightness, chest pain, and arrhythmia, it is due to misalignment of the intervertebral joints and narrowing of the intervertebral foramina to irritate the nerve roots. The intercostal nerves from the spinal cord have only one level of neurons, and once the bone and joints are reset and the nerve root irritation is removed, the intercostal muscle spasm can be relieved, and the chest tightness and chest pain can disappear. Arrhythmia sometimes slow recovery, because the sympathetic preganglionic fibers through the intervertebral foramen when stimulation or compression and damage, the preganglionic fibers belong to the β class of sheathed fibers, its fibers are fine, the transmission speed is slow, the latency period is long, the damage is serious when it can cause demyelination changes, and at the same time, sympathetic nerves from the lateral angle of the spinal cord to the heart for the second level of neuron, the medium of secretion of the recovery than the peripheral nerves to be a little slower. The condition of these patients is more complicated, because the root cause of their symptoms lies in the nerves, so in addition to lifting the lesions, it is more necessary to regulate the nervous system in order to restore normalcy, otherwise the nerve function can not be restored, the symptoms will only recur, and it is difficult to cure.