Patients who take sleeping pills still can’t sleep, the reason may be the following: 1. Patients who have severe anxiety and depression will not respond well to sleeping pills and may not be able to sleep even after taking sleeping pills, which is very common in clinical practice. Such patients should be given anti-anxiety and antidepressant treatment at the same time to be effective, to improve the patient’s sleep, such as giving the patient oral Dextran or escitalopram oxalate, olanzapine type of drugs, improve the patient’s mood after sleeping pills can be effective, the patient will be able to sleep. The patient will be able to fall asleep on his own even if he does not take sleeping pills. 2, the patient can not sleep after taking sleeping pills, and the patient has a certain relationship with long-term sleeping pills, and has a certain resistance to drugs, so the effect of taking sleeping pills is not good.