Thyroid peroxidase antibody 1000 is more important. However, the severity of the condition also depends on the altered level of thyroid function and its effect on the body, and consultation with a doctor is recommended. Thyroid peroxidase antibodies are higher than normal, suggesting that the patient may have thyroid-related antibodies that destroy their own thyroid tissue, and there are no medications available at this stage to treat these antibodies, so it is important to monitor thyroid function if the body shows positive thyroid peroxidase antibodies. If the antibody value is 1000, further examination is needed, mainly to check the thyroid function and determine whether there is hypothyroidism or hyperthyroidism. Therefore, when a patient has a thyroid peroxidase antibody of 1000, it is recommended that the patient go to the hospital for a timely examination.