Hepatitis B 1, 2, and 5 positive refers to the results of the five hepatitis B tests, which generally correspond to hepatitis B surface antigen, hepatitis B surface antibody, and hepatitis B core antibody. It is rare to see these three items positive at the same time, while the other two items are negative. The reason is that surface antigen and surface antibody do not appear at the same time, but only after the hepatitis B virus has infected the body and started to heal. Because surface antigen and surface antibody are a pair, the presence of antigen indicates a viral infection and no antibodies appear, while the presence of antibodies indicates that the body’s immune system is clearing the surface antigen of hepatitis B. However, because the surface antigen has not been completely cleared, a positive surface antigen can still be seen in the presence of a positive surface antibody. If the test is repeated in another week or so, it is likely that the surface antigen will turn negative and only the surface antibodies will be positive, which means that hepatitis B has been cured. Therefore, in this case, the quantification of the five hepatitis B tests should be repeated in about a week’s time.