Pioneer VI, also known as cefradine, belongs to the first generation of cephalosporins. Pioneer VI has a strong bactericidal effect on Gram-positive cocci and a weaker effect on Gram-negative bacteria. It has bactericidal effect on Streptococcus, Staphylococcus aureus, Staphylococcus epidermidis and Pneumococcus, and is effective on Meningococcus and Diphtheria bacillus. It has a strong killing effect on drug-resistant Staphylococcus aureus Klebsiella pneumoniae. It has antibacterial effect on Escherichia coli, and some of the Aspergillus. It is mainly used clinically for respiratory tract infections, genitourinary tract infections, intestinal and soft tissue infections caused by sensitive bacteria.