If you feel a lot of granules at the base of the thighs, it is possible that the patient has an allergic reaction in the skin area, due to which the occurrence of allergies may produce pronounced papules, pimples, etc. These inflammatory granules are mainly due to the inflammatory proliferative reaction due to allergic factors. Such granules may also be subcutaneous skin damage, such as the appearance of subcutaneous fat granules or the formation of subcutaneous nodules. The causes of these skin lesions are complex, and the formation of inflammatory papules or pimples may be due to eczema or atopic dermatitis, which may be accompanied by itching.