Sore throat is a common clinical symptom, which may be caused by acute pharyngitis, acute suppurative tonsillitis, acute epiglottitis and other diseases, and the best treatment is to choose the medicine according to the specific situation. 1. Acute pharyngitis: due to upper respiratory tract infection, resulting in inflammation of the pharynx and lymphoid follicular hyperplasia. It can be treated with antiviral and antibacterial drugs or proprietary Chinese medicines with antiviral and antibacterial effects; anti-inflammatory drugs such as amoxicillin and cephalosporins can be used. Proprietary Chinese medicines can be used, such as busulfan anti-inflammatory tablets. 2. Acute suppurative tonsillitis: there is yellowish-white pus or yellowish-white cheese-like pus on the surface of tonsils. Mouthwash can be used to remove the pus, and at the same time oral or intravenous injection of penicillin and cephalosporin antibiotics, such as amoxicillin clavulanate potassium, cefuroxime treatment of inflammation, according to the severity of the disease to determine the route of administration of drugs. 3. Acute epiglottitis: manifested as sore throat with obvious swallowing pain, accompanied by respiratory effects and dyspnea. Penicillin and other antibiotics can be used in conjunction with the use of hormone drugs to relieve the swelling. Sore throat, it is recommended to go to the hospital in time to clarify the cause of the disease, according to the specific circumstances of the symptomatic treatment, under the guidance of the doctor to use drugs.