Sexual life will not affect the potency of the quadrivalent vaccine, so you can have normal sexual life after receiving the quadrivalent vaccine, but you need to pay attention to contraception and avoid excessive exertion. Quadrivalent vaccine usually refers to quadrivalent cervical cancer vaccine, which is administered in the upper arm and does not affect normal sexual life, nor does sexual life affect the functioning of the vaccine. However, it should be noted that the quadrivalent vaccine is still lacking in clinical studies on women preparing for pregnancy, so it takes half a year after the one-year vaccination to prepare for pregnancy, so it is necessary to take good contraceptive measures. Avoid overwork after vaccination. To summarize, after the quadrivalent vaccination, you can have a normal husband-wife relationship, take proper contraceptive measures, and avoid overwork. After vaccination, you need to avoid water on the wound area and avoid spicy and stimulating diet.