Cervical atypical squamous cells of unknown significance, indicating cytomorphological changes, suggesting squamous intraepithelial lesions, but not enough to make a definite diagnosis, or too few cells with diagnostic significance, mainly may be related to inflammation, intrauterine device, smear taking bad fixation, precancerous lesions, etc.: 1, inflammation: chronic inflammation of the uterine cervix, the cervix can be erosion-like changes, causing cervical atypical squamous cells of unknown significance. Treatment mainly includes medication, such as Direxuline local medication, and physical therapy, such as laser, freezing, and if necessary, surgery, such as cervical conization; 2, intrauterine device: atypical squamous cells can be found when doing TCT examination, if there are no abnormal symptoms, it is recommended to review, if there are symptoms such as abnormal bleeding, you should go to the hospital in time to clarify the cause and carry out treatment; 3, smear Poor fixation: It may be caused by poor fixation of the smear, thus affecting the examination results, which can be rechecked if necessary; 4. Precancerous lesions: HPV examination and colposcopy for biopsy are recommended. If the pathological results suggest inflammation, regular physical examination is recommended. If the cervical colposcopy suggests high-grade squamous intraepithelial lesion, further cervical conization surgery is needed, if it is low-grade squamous intraepithelial lesion, it needs to be reviewed after six months. The significance of cervical atypical squamous cells is not clear and does not suggest cervical lesions. Women should pay attention to health check-ups and have regular check-ups.