Tattoo blisters may be caused by improper operation or allergy, and should be avoided to rupture the blisters, and timely and according to the cause of the appropriate treatment. Tattoo operation aseptic operation is not standardized or tattoo after improper care leading to infection, local soft tissue swelling may produce severe tension blisters. At this time should be sterilized with a sterile syringe to draw out the liquid within the blisters, after the external use of mupirocin ointment and other topical drugs to avoid further infection. If the blisters appear after the tattoo and accompanied by obvious itching of the skin, generally due to allergies. At this time should go to the hospital in a timely manner, clear cause for targeted treatment. Allergies can be oral antihistamine drugs, such as loratadine, etc., to inhibit the allergic reaction, serious cases of glucocorticoids such as dexamethasone treatment. When the blisters appear to break, must pay attention to keep the wound clean, to avoid secondary damage. The appearance of the above symptoms should be timely to the regular hospital, please specialists to deal with trauma, to avoid blind treatment led to the aggravation of the condition.