High triglycerides and cholesterol can be lowered through lifestyle modification and medication, and the specific treatment needs to be standardized under the guidance of a doctor. 1. Lifestyle modification: high triglycerides and cholesterol are closely related to dietary habits, it is recommended to have a light diet, less oil and salt, avoid overeating, and at the same time, it is also recommended to have reasonable exercise and regular work and rest to improve triglyceride and cholesterol levels. 2. Medication: If lifestyle adjustments cannot effectively reduce triglyceride and cholesterol levels, you can take triglyceride-lowering drugs and cholesterol-lowering drugs. Triglyceride-lowering drugs include fenofibrate, benzapentane, etc., and cholesterol-lowering drugs include atorvastatin, simvastatin, etc. In addition, you can also choose niacin-type drugs. In addition, niacin drugs such as acipimox and niacin; cholesterol absorption inhibitors such as ezetimibe; and bile acid sequestrants such as colesevelam are also available for treatment. Due to individual variability, drugs are not absolutely effective and safe, so it is necessary to follow the doctor’s instructions to standardize the treatment. Adverse reactions such as dizziness, nausea, skin rash, etc. are recommended to consult a doctor in time, and drug allergy is prohibited.