Hematospermia in middle-aged and old people should first clarify the cause of the disease, and then according to the cause of the disease to choose antibiotic treatment, endocrine treatment, symptomatic treatment, vesicoscopy treatment and other methods to carry out treatment. 1. Antibiotic treatment: for patients with hemospermia caused by inflammation and infection, sensitive antibiotics can be selected through bacterial culture for treatment, commonly quinolones, macrolides, cephalosporin antibiotics. 2. Endocrine therapy: for advanced prostate cancer, posterior urethral adenoma and other neoplastic diseases leading to hemospermia, endocrine drugs can be used, such as finasteride and so on. 3. Symptomatic treatment: the main use of hemostatic drugs to alleviate the symptoms of hematospermia, commonly used drugs such as tranexamic acid and carbachol. 4. Vesicoscopic treatment: for some cases which are not cured for a long time or accompanied by seminal vesicle stones, vesicoscopy can be used for examination and treatment, which on one hand can help to make a clear diagnosis, and on the other hand can flush the seminal vesicles and combine with drug treatment. If you have hematospermia in middle-aged or old age, first of all, you should carry out a systematic examination to find out the cause of the disease, and then according to the examination results, you should actively cooperate with the treatment under the guidance of the doctor, and the drugs should be applied under the guidance of the doctor.