Hemospermia is one of the more common male diseases, mainly manifested by the discharge of semen that is bloody, sometimes interspersed with blood or blood clots. Usually, hematospermia is considered to be a benign self-limiting disease that only requires simple conservative treatment such as anti-infection and hemostasis to heal. The mucous membrane of the seminal vesicles has a rich layer of tiny blood vessels and is therefore highly susceptible to injury and bleeding. During orgasmic ejaculation, the smooth muscles of the vas deferens, seminal vesicles, ejaculatory ducts and posterior urethra contract violently, and small blood vessels are prone to rupture and bleeding resulting in hematospermia. Hemosperm is closely related to excessive engorgement of the seminal vesicles and inflammatory infection. Damage to the seminal vesicles such as excessive indulgence or prolonged non-exhaustion of delicacy makes the seminal vesicles filled and swollen, and inflammation of the seminal vesicles can make the annual membrane of the seminal vesicles congested and edematous, and hemosperm can occur during ejaculation. However, there are still 1/3 of patients with “prolonged hematospermia” or “recalcitrant hematospermia” in clinical practice, and the use of various conventional conservative methods is ineffective or recurrent, causing great mental stress and family distress to patients. The main causes of hematospermia are seminal vesicle, ejaculatory duct, vas deferens and other seminal tract infections and stones, prostate capsule stones or infections, seminal tract tumors, congenital malformations of the seminal tract, seminal cysts, posterior urethral inflammation, prostatitis (tumors), hemorrhagic disorders and systemic disorders, etc., and clinical experience has concluded that most of the bleeding comes from seminal vesicle, ejaculatory duct and prostate capsule disorders. The diagnostic criteria for hematospermia: 1. Semen is pink, red, light brown or interspersed with blood or blood clots under the naked eye. 2, Semen routine: microscopically visible red blood cells. 3.It may be accompanied by painful ejaculation, discomfort of perineum, frequent urination, urgent urination, painful urination, seminal emission, hypogonadism, premature ejaculation and other symptoms. 4, persistent hematospermia: after varying periods of anti-infection and hemostatic drug treatment, the onset of hematospermia persists for more than 3 months with poor results. Clinical cure criteria: disappearance of hematospermia by naked eye, no red blood cells in routine semen examination, and no recurrence for 3 months of follow-up. Selective tests for hematospermia: 1, semen routine, seminal plasma fructose, etc., and if necessary, bacterial culture and drug sensitivity of semen. 2, Prostate-specific antigen (PSA). 3, Transrectal ultrasound examination and/or magnetic resonance: prostate, ejaculatory duct, seminal frenulum, seminal vesicles 4, Seminal vesicle microscopy: the site and cause of bleeding can be clarified, as well as treatment such as direct drug irrigation and perfusion under seminal vesicle microscopy, release of obstruction at the distal end of the seminal tract, holmium laser hemostasis, laser lithotripsy or cauterization of polyps. Treatment of hematospermia: 1. Improvement of lifestyle: light diet, less spicy and stimulating food, tobacco and alcohol, moderate and regular sex life. 2.Conservative treatment such as anti-inflammatory, blood activation and hemostasis: cephalosporins, quinolones or macrolides antibiotics, dexamethasone, finasteride (Paulownia), pancreatic kininogenase, etc. 3.Treatment by Chinese herbal medicine: Qinghe Tonglin Tang, Guizhi Fu Ling Wan, Erzhi Dihuang Tang, Shao Abdominal Expelling Blood Stasis Tang, Liu Wei Dihuang Wan, Ba Wei Ren Qi Wan, Si Wei Tang, Gui Shen Wan, Si Miao Wan (Tang), Ginseng Yang Rong Wan, etc. 4. Diagnosis and treatment of vesiculoscopy: see the author’s lecture on “vesiculoscopy” for details. P.S.: Persistent hematospermia It is a clinical condition that is very tedious and stressful for patients and their sexual partners. Clinical experience shows that intractable hematospermia is mainly caused by chronic inflammation of the seminal vesicles or secondary vesicular calculi. Most bacterial infections of the seminal vesicles spread to the patient’s ejaculatory ducts, resulting in poor drainage of the ejaculatory duct opening, reflexively causing the migration of seminal vesicle inflammation and causing hematospermia. In addition, seminal vesicle stones and small prostate capsule stones are also important factors that lead to recurrent episodes of hematospermia and the formation of persistent hematospermia. Ultrasound and magnetic resonance examination can reveal lesions in the seminal vesicles, ejaculatory ducts, prostate and its small sacs, such as dilated seminal vesicles and/or ejaculatory ducts and stones, and cystic stones in the prostate. This is a specific indication for “seminoscopy” examination, further diagnosis and treatment. Seminoscopy can eliminate stones, dilate the obstruction of the seminal ducts and thus improve the flow and drainage of the seminal ducts, while local irrigation and perfusion can improve the local environment and blood circulation, etc. For the clinical examination are not seen infection ah, stenosis, tumor, stones, etc., alone is the performance of hematospermia. There is no way to start on treatment. Traditional Chinese medicine is unique in the treatment of intractable hematospermia.