Colds can be categorized into the common cold and influenza, both of which are caused by viral infections. A runny yellow nose may be associated with a viral cold secondary to a bacterial infection. Colds are caused by viral infections. The virus infects the mucous membrane of the nasal cavity, thus causing congestion and edema of the mucous membrane of the nasal cavity and an increase in the secretion of the glands, resulting in the symptom of runny nose, which is usually clear and watery. If there are symptoms such as yellow runny nose, it may be related to secondary bacterial infection of the nasal mucosa, and the leukocytes in the nasal mucosa phagocytosis of bacteria after the cleavage, necrosis and necrotic mucosa and exudate to form a yellow runny nose outflow. If the cold has a basis for bacterial infection, it can be treated with anti-infective therapy, such as cefdinir, cefixime and other drugs. Yellow nasal discharge may also be caused by other diseases, if the symptoms are not relieved or aggravated, it is recommended that the patient go to the hospital in time to improve the examination, a clear diagnosis, after diagnosis, follow the doctor’s instructions to take standardized treatment.